July - September 2021, Volume 17, Issue 3

Roman G, Teodorescu G

Increased Prevalence of Cardiovascular Risk Factors in Newly Diagnosed Type 2 Diabetes Patients – a Retrospective Study

Acta Endo (Buc) 2021, 17 (3): 331-336
doi: 10.4183/aeb.2021.331

Context. Identification of CV risk factors from T2DM diagnosis allows optimization of treatment to prevent CV complications and death. Objective. The primary objective of the study was to describe the CV risk factors in patients with T2DM at the time of diagnosis and/or therapeutic specific measures taken. Design. This was a non-interventional, multicenter, retrospective chart review of newly diagnosed patients with T2DM in 49 study centers in Romania. Subjects and Methods. Adults with a diagnosis of T2DM between January - December 2014. Statistical analysis used appropriate descriptive methods. Results. 1218 patients were included, mean age (SD) at diagnosis was 59.16 (10.87) years. Half of the patients (54%) presented obesity and 47.7% of patients had arterial hypertension. Overall, 76.2% of subjects had LDLcholesterol ≥ 100 mg/dL, and 59.1% had triglycerides ≥ 150 mg/dL. The mean glycemia was 198.8 mg/dL (78.3) and 50.2% of patients had HbA1c ≥7%. Sedentary lifestyle in 73.8% of the cases, and 91.3% unhealthy eating habits reported. In addition to diet, 82.2% of patients received antidiabetes treatment, 62.6% lipid-lowering, and 66.6% antihypertensive medication. Conclusion. This retrospective study showed a high prevalence of CV risk factors and/or established CV disease at the time of T2DM diagnosis in Romania.

Keywords: Type 2 Diabetes, cardiovascular risk factors, obesity, arterial hypertension, dyslipidemia, HbA1c, insulin resistance.

Correspondence: Adrian Zaharia MD, AstraZeneca Romania, Medical Department, Bucharest Business Park, 12 Menuetului Street, building D, 1st floor, district 1, Bucharest, 013713, Romania, E-mail: adrian.zaharia@astrazeneca.com