October - December 2005, Volume 1, Issue 4

Ionescu R, Opris D

Severe osteoporosis with vertebral fractures in a young woman with Behcet's disease

Acta Endo (Buc) 2005, 1 (4): 473-480
doi: 10.4183/aeb.2005.473

We describe a case of severe osteoporosis with vertebral fractures in a 30-year-old male with very active Beh?et?s disease treated for nine months with high doses of Prednisone. He was admitted to our department because of classical manifestations of the autoimmune disorder (bipolar aphthous) and also for acute mechanical back pain developed after a minor fall. The X-ray evaluation revealed a spinal fracture confirmed by the CT scan. The DXA evaluation revealed a T-score of -3.4 with an identical Z-score. The patient was diagnosed with severe secondary (glucocorticoid induced) osteoporosis with vertebral fracture and active Beh?et disease.

Keywords: Beh?et?s disease, rheumatologic disorder, vertebral fracture, glucocorticoids, osteoporosis

Correspondence: Daniela Opris, ?Sf. Maria? Clinical Hospital, ?Carol Davila? University of Medicine and Pharmacy, Research Center on the Pathology and Treatment of the Systemic Rheumatic Diseases, Bucharest, Romania, phone: +40.21.2223550, email: danaopris0103@yahoo.com