October - December 2010, Volume 6, Issue 4

Laway BA, Shah T, Bahir M, Dada A, Zargar AH

Acute onset psychosis following steroid replacement in Sheehan's syndrome

Acta Endo (Buc) 2010, 6 (4): 533-538
doi: 10.4183/aeb.2010.533

Psychosis following steroid replacement in Sheehan's syndrome is rarely encountered. We present the clinical course of two patients who developed severe psychosis after starting them on low dose prednisolone. Psychosis subsided after either stopping or decreasing the dose together with use of antipsychotic medications. Glucocorticoids restarted a week later in low doses were well tolerated. Both the patients were reviewed after three months and were psychosis free.

Keywords: Sheehan's syndrome; Hypopituitarism; Steroids; Psychosis

Correspondence: Bashir Laway, Sher-I-Kashmir Institute of Medical Sciences - Endocrinology, B2 Faculty Quaters, SKIMS, Srinagar 19000, India, Email: drlaway@gmail.com