July - September 2011, Volume 7, Issue 3

Paun S, Carsote M, Poiana C, Neamtu C, Ganescu R,Negoi I, Paun DL

Laparoscopic Surgery - A Feasible Treatment in Morris Syndrome

Acta Endo (Buc) 2011, 7 (3): 385-394
doi: 10.4183/aeb.2011.385

Morris Syndrome is a pathological condition which needs a special approach regarding both diagnosis and treatment\r\nbecause of its rarity. While the diagnosis is based on karyotype test, the treatment should follow the idea of harmless and cosmetic benefits as well as complete gonads removal. This paper is presenting the usefulness and advantages of minimally invasive surgery as a feasible treatment for such a disease. A retrospective study was performed for two patients with Morris Syndrome, admitted to\r\nthe ?CI Parhon? National Institute of Endocrinology, Bucharest, Romania, followed-up for 4 - 16 years, and operated to the Department of Surgery, Emergency\r\nHospital, Bucharest, Romania. Patients with primary amenorrhea have been clinically observed and three patients\r\nwith 46, XY karyotype have been identified as Morris Syndrome cases needing surgical removal of the intraperitoneal gonads because of the risk of malignant transformation. A minimally invasive surgical technique has\r\nbeen chosen for proper treatment: the anterior transperitoneal laparoscopic approach. The surgery was adapted to every case, in according with preoperative imagistic diagnosis of the intraperitoneal testes\r\n(localization, dimensions, adjacent organs involvement, surgical access). No postoperative complications were noticed and specimens' pathology confirmed the final\r\ndiagnosis. Cosmetic benefits were achieved for every young patient as well as rapid postoperative recovery (discharge after 48 hours). The authors concluded that Morris Syndrome patients could benefit from the laparoscopic surgery which is a feasible, safe and proper treatment for such cases.

Keywords: laparoscopic surgery, androgen insensitivity syndrome, testis\r\nmalignancy

Correspondence: Sorin Paun MD, PhD, Bucharest Emergency Hospital, Dpt. of\r\nSurgery,-Bucharest, Romania. Email: drspaun@yahoo.com