October - December 2011, Volume 7, Issue 4

Celik O, Buyuktas D, Acbay O

Alternate Days Treatment with Teriparatide in Postsurgical Hypoparathyroidism

Acta Endo (Buc) 2011, 7 (4): 545-550
doi: 10.4183/aeb.2011.545

The conventional treatment of hypoparathyroidism consists of vitamin D analogues in combination with oral calcium\r\nsupplementation. This treatment modalities induce chronic hypercalciuria which leads to nephrocalcinosis, nephrolithiasis and renal insufficiency. Here we report the case of a 32-year-old woman who developed hypocalcemia and hypercalciuria under treatment with high doses of vitamin D\r\nanalogs and oral calcium. She had cerebral calcification, nephrocalcinosis under this treatment. Stable calcium levels were achieved with synthetic human parathyroid hormone treatment that was given in alternate days. PTH appears to be an alternative and effective treatment in hypoparathyroidism.

Keywords: hypocalcemia, hypoparathyroidism, synthetic human parathyroid hormone

Correspondence: Prof. Dr. Ozer Acbay, Cerrahpasa Tip Fakultesi, Ic Hastaliklari Anabilim Dali Endokrinoloji-Metabolizma ve Diyabet Bilim Dali, 34303 Cerrahpasa, Istanbul, Turkey, Tel: 90 532 445 59 96, Fax: 90 212 233 38 06, Email: oacbay@operamail.com