The International Journal of Romanian Society of Endocrinology / Registered in 1938

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October - December 2011, Volume 7, Issue 4
Case Report

Cristea C, Plaiasu V, Ochiana D, Draghicenoiu Neagu R, Gherlan I, Mardarescu M

Sexual Ambiguity Associated with "in utero" Antiretroviral Exposure

Acta Endo (Buc) 2011, 7 (4): 551-560
doi: 10.4183/aeb.2011.551

Mixed gonadal dysgenesis and ovotesticular disorders of sex development, are rare conditions that occur sporadically,\r\nwith unknown prevalence. Clinical manifestation of this diseases is sexual ambiguity. The authors present a pediatric\r\ncase with sexual ambiguity and karyotype 45, X/46, XY, the child of a HIV-positive mother receiving multiple antiretroviral treatments for a period of 16 years.

Keywords: antiretroviral therapy, side effects, mixed gonadal dysgenesis, cytogenetics

Correspondence: Cosmina Cristea, IOMC - pediatrics 120 Lacul Tei Boulevard Bucharest 020395 Romania Tel: 0212422713, Email: