April - June 2012, Volume 8, Issue 2

Isildak SM, Ayturk S, Bascil S, Tutuncu N

Insulin Glargine in Gastrostomy Feeding

Acta Endo (Buc) 2012, 8 (2): 257-263
doi: 10.4183/aeb.2012.257

Context. For control of blood glucose in diabetic patients on enteral feeding either insulin infusion or multiple insulin injections are used. However, both of these\r\nmethods necessitate a very close follow-up and are not easy to apply during home care.\r\nObjective. In this study we aimed to see whether insulin glargine once daily is proper for glucose regulation in enterally fed diabetic patients.\r\nDESIGN: Insulin glargine is given to enterally fed diabetic patients and they are followed up for three months.\r\nSubjects and methods. Thirteen diabetic stroke patients with PEG are involved in the study. Treatment of these patients is switched from insulin infusion or multiple insulin injections to once daily insulin glargine and they are followed up for 3 months.\r\nResults. Mean blood glucose values are improved with once daily insulin glargine regimen. HbA1c decreased from 7.2% ? 1.5 5. to 6.7% ? 0.8 with insulin glargine. Daily insulin requirement of the patients is significantly decreased as well. A significant decrease in the hypoglycemic episodes is\r\ndetected with glargine (p<0,0001).\r\nConclusion. Insulin glargine once daily is a safe and effective regimen for diabetic patients with PEG.

Keywords: insulin glargine, enteral feeding, stroke

Correspondence: Serife Mehlika Isildak, Baskent Uni. - Endocrinology and Metabolism, Maresal Fevzi Cakmak Cad 10. sokak Bahcelievler Ankara 06490,Turkey, Email: mehlikaisildak@gmail.com