April - June 2012, Volume 8, Issue 2

Surcel M, Stamatian F

Folliculogenesis Disturbances within the Polycystic Ovarian Syndrome and Possible Consequences on Oocyte Quality

Acta Endo (Buc) 2012, 8 (2): 267-287
doi: 10.4183/aeb.2012.267

The debates on the quality of oocytes in PCOS patients are still heated and controversy is very intense, with a wide\r\nspectrum of variations proposed. The present study aims at analyzing the main factors altered in the economy of PCOS\r\npathogenesis, mainly those involved in the folliculogenesis dysfunction, and, also, to evaluate their potentially detrimental role upon oocyte quality.\r\nIndividual elimination of the more prominent follicular factors, at least through deviation from the normal, as compared to the degree of oocyte maturation did not manage to be cleared in unequivocal terms for any of them. Most interestingly, the spectrum of answers varied from\r\nprofoundly modified values to the absence of any differences whatsoever, inevitably leading, as sole functional conclusion, to assuming the extremely heterogeneous\r\ncharacter of this affection.

Keywords: PCOS, oocytes, folliculogenesis

Correspondence: Florin Stamatian, ?Iuliu Hatieganu? University of Medicine and\r\nPharmacy Cluj-Napoca - Ginecolgie I, 3-5 Clinicilor Cluj-Napoca 400006, Romania, Email: florin_stamatian@yahoo.com