January - March 2014, Volume 10, Issue 1

Jinga M, Jurcut C., Vasilescu F., Balaban V.D., Maki M., Popp A

Celiac Gluten Sensitivity in an Adult Wman with Autoimmune Thyroiditis

Acta Endo (Buc) 2014, 10 (1): 128-133
doi: 10.4183/aeb.2014.128

We present the case-report of a 56 years-old woman with hypothyroidism due to autoimmune thyroiditis. The family history was positive for biopsy proven celiac disease (CD) in her daughter. The patient declared gluten-containing diet and was completely asymptomatic regarding gastrointestinal tract. The serological screening for CD reflected an activity of the disease by the presence of antiendomysial antibodies (EMA). Consequently, an upper gastrointestinal endoscopy was performed and biopsy specimens were obtained. The standard histopathological examination was unremarkable for a defined CD. However, the results of immunohistological techniques showed intestinal IgA deposits compatible with early developing CD. In patients with family history of CD, even without any suggestive symptoms, high index of suspicion regarding CD should be kept even more in those associating other autoimmune disease.

Keywords: autoimmune thyroiditis, latent celiac disease, antiendomysial antibodies, intestinal IgA deposits.

Correspondence: Mariana Jinga MD, “Dr. Carol Davila” Central University Emergency Military Hospital, “Carol Davila” University of Medicine and Pharmacy, Gastroenterology, 88 M.Vulcanescu street, Sector 1, PO Box 4-16, 010825, Bucharest, Romania, E-mail: mariana_jinga@yahoo.com