October - December 2014, Volume 10, Issue 4

Dass J, Gupta A, Kothakota SR, Agarwal PK, Bhargava M

Carbimazole Induced Agranulocytosis with Marked Marrow Plasmacytosis Mimicking Multiple Myeloma

Acta Endo (Buc) 2014, 10 (4): 671-677
doi: 10.4183/aeb.2014.671

Carbimazole is a common drug used to treat hyperthyroidism. Agranulocytosis is a known adverse effect of these anti-thyroid drugs but plasmacytosis simulating multiple myeloma is a very uncommon manifestation of this drug. We report here the case of a patient of hyperthyroidism who developed febrile neutropenia while on carbimazole with the preliminary marrow findings simulating plasma cell myeloma.

Keywords: marrow plasmacytosis, agranulocytosis, carbimazole, anti-thyroid drugs, vasculitis.

Correspondence: Aastha Gupta MD, Sir Ganga Ram Hospital - Hematology, Rajendra Nagar, New Delhi, 110060, India, E-mail: draasthagupta83@gmail.com