October - December 2015, Volume 11, Issue 4

Figueroa AL, Hanzu F, Gomis R

Nutrition and the Clock Gene

Acta Endo (Buc) 2015, 11 (4): 489-491
doi: 10.4183/aeb.2015.489

A number of recent studies in animals and humans have linked energy regulation and the circadian clock at the molecular, physiological and behavioural levels, concluding that disruption of clock genes results in metabolic dysregulation. The search to understand the causes of obesity and diabetes and the development of new therapeutic strategies have mostly focused on caloric intake and energy balance. In this review, we present a global overview of the circadian clock as a critical interface between nutrition and homeostasis.

Keywords: Nutrition, clock genes, circadian rhythms.

Correspondence: Ramon Gomis MD, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer del Rosselló, 149, 08036 Barcelona, Spain, E-mail: ramon.gomis@idibaps.org