The International Journal of Romanian Society of Endocrinology / Registered in 1938

in ISI Thomson Master Journal List

October - December 2017, Volume 13, Issue 4
Case Report

Bilge M, Adas M, Yesilova A, Gokden Y, Bayraktarli RY, Helvaci A

Osteomalacia as a Result of Urinary Diversion

Acta Endo (Buc) 2017, 13 (4): 491-493
doi: 10.4183/aeb.2017.491

A 54 years old man, who had undergone a cystectomy and urinary diversion surgery 31 years previously, complained of progressive generalized bone pain, muscle weakness and walking abnormality for six months. Laboratory investigations revealed elevated alkaline phosphatase, high serum chloride level and metabolic acidosis. Osteomalacia was suspected due to clinical and laboratory findings. Osteomalacia due to hyperchloremic metabolic acidosis is a complication of urinary diversion. Regular monitoring of pH, chloride, bicarbonate, and calcium-phosphorus metabolism is therefore essential for early diagnosis and treatment.

Keywords: osteomalacia, urinary diversion, hyperchloremic metabolic acidosis

Correspondence: Muge Bilge MD, Okmeydani Education and Research Hospital, Internal Medicine, Darulaceze cad sisli, Istanbul, 34000, Turkey, E-mail: