The International Journal of Romanian Society of Endocrinology / Registered in 1938

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January - March 2020, Volume 16, Issue 1
Letter to the Editor

Gemcioglu E, Karabuga B, Ercan A, Erden A

A Case of Inappropriate Antidiuretic Hormone Secretion Syndrome Associated with Covid-19 Pneumonia

Acta Endo (Buc) 2020, 16 (1): 110-111
doi: 10.4183/aeb.2020.110

At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia in China and it spread quickly to other countries. Although Covid-19 causes severe pneumonia, it is known that it can be associated with different diseases and prognosis of disease can be due to many of disorders such as hyponatremia. A 65-year-old female patient with sarcoidosis, cronic obstructive lung disease, hypertension and congestive heart failure presented to the emergency department with shortness of breath and fever. Oropharyngeal swab for Covid-19 PCR test was positive. After the initiation of treatment, the patient developed hyponatremia. This case is remarkable because there is no reported case of Covid-19 and inappropriate ADH syndrome coexistence and it demonstrates that there may be a correlation between Covid-19 infection prognosis and hyponatremia.

Keywords: Inappropriate Antidiuretic Hormone Secretion Syndrome (SIADH), Covid-19.

Correspondence: Emin Gemcioglu MD, Ankara City Hospital, Ministry of Health, Department of Internal Medicine, Üniversiteler, Bilkent Blv. No.1, 06800, Çankaya, Ankara, 06105, Turkey, E-mail: