The International Journal of Romanian Society of Endocrinology / Registered in 1938

in ISI Thomson Master Journal List

Acta Endocrinologica(Bucharest) is live in PubMed Central

April - June 2020, Volume 16, Issue 2
Endocrine Care

Musina AM, Hutanu I, Scripcariu DV, Anitei MG, Filip B, Hogea M, Radu I, Gavrilescu MM, Panuta A, Buna-Arvinte M, Moraru V, Scripcariu V

Surgical Management of the Adrenal Gland Tumors - Single Center Experience

Acta Endo (Buc) 2020, 16 (2): 208-215
doi: 10.4183/aeb.2020.208

Context. Incidentally discovered solid adrenal tumors must be evaluated from two points of view: the risk of malignancy and the secretory feature. Objective. Our aim was to evaluate the surgical technique option in relation with clinical and histopathologic features. Design. We performed a retrospective study that included patients with adrenal gland tumors. Subjects and methods. All patients were operated between 2012 and 2019 by the same surgical team in a single center. Results. The batch included 102 patients with adrenal tumors operated through open surgery (OS, n=41) and laparoscopic surgery (LS, n=61). Tumor localization was especially on the right adrenal gland (n=52, 50.98%). Primary origin of the adrenal gland tumors was in 82 cases (80.39%) and a metastatic origin in 16 cases. Average dimension for surgical resected tumors was 4.02 cm (0.9-12 cm) for the LS group as compared to 7.22 cm (1.3-19 cm) for OS group with a predominant type of surgery represented by adrenalectomy and a conversion rate of 2.94%. The hospital stay was 7.22 days (5-12 days) in the LS group versus 12.72 days (6-57 days) in OS group with significant differences (p<0.01). Also, the postoperative recovery was significantly different (6.5 days versus 2.62 days, p<0.01). Conclusion. Laparoscopic approach represents the gold standard in adrenal gland tumors less than five centimeters in size. Adrenalectomy is mostly performed by LS and adenoma is the most frequent histopathologic type, while pheochromocytoma is operated through OS. LS has a significantly reduced hospitalization and postoperative stay compared to OS.

Keywords: adrenal gland, adrenalectomy, primary tumor, metastatic tumor.

Correspondence: Drago?-Viorel Scripcariu MD, “Grigore T. Popa” University of Medicine and Pharmacy, Surgery, Buna Vestire 8, Ia?i, 700455, Romania, E-mail: