The International Journal of Romanian Society of Endocrinology / Registered in 1938

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Acta Endocrinologica(Bucharest) is live in PubMed Central

July - September 2020, Volume 16, Issue 3
Case Report

Mezoued M, Habouchi MA, Azzoug S, Mokkedem K, Meskine D

Juxtaglomerular Cell Cause of Secondary Hypertension in an Adolescent

Acta Endo (Buc) 2020, 16 (3): 359-361
doi: 10.4183/aeb.2020.359

Reninoma (juxtaglomerular cell tumor) is a rare cause of renin-mediated hypertension. We reported a 18 year old woman with history of hypertension for 3 years. Laboratory findings showed severe hypokalemia and markedly increased levels of renin and aldosterone. Kidney ultrasonography, abdominal computed tomography and magnetic resonance imaging revealed a small mass in the middle region of the right kidney. The patient underwent nephron-sparing surgery; immunohistochemical results demonstrated typical features of reninoma. Postoperatively, blood pressure and potassium levels were normal at 1 month follow-up.

Keywords: hypertension, renin, reninoma, juxtaglomerular cell tumor, hypokalemia.

Correspondence: Mouna Mezoued MD, University of Algiers Faculty of Medical Sciences, Department of Endocrinology and Metabolism, Algiers, Alger, 16000, Algeria, E-mail: