July - September 2021, Volume 17, Issue 3

Anghel RM, Serbanescu GL

Actualities in Involvement of Estrogens in the Pathogenesis of Colorectal Cancer

Acta Endo (Buc) 2021, 17 (3): 400-403
doi: 10.4183/aeb.2021.400

Gastrointestinal effects of estrogens are emerging as an important topic in colorectal cancer management. Current research demonstrated the link between inflammation and this malignancy, so important estrogen dependent mediators of the inflammatory response have been identified. Radioresistance and chemoresistance still represent an important cause of therapeutic failure in colorectal cancer and lead to further studies of colorectal carcinogenesis and predictive markers.

Keywords: Colorectal cancer, Estrogens, Pathogenesis.

Correspondence: Georgia Luiza Serbanescu MD, “Carol Davila” University of Medicine and Pharmacy, Faculty of General Medicine, 252 Fundeni Street, Bucharest, 022328, Romania, E-mail: luizaserbanescu@yahoo.com