The International Journal of Romanian Society of Endocrinology / Registered in 1938

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April - June 2022, Volume 18, Issue 2
Endocrine Care

Singh P, Arora S, Goyal A, Mittal N, Singh A, Sharma S, Shanthaiah DM, Dardi IK

Influence of the Duration of Diabetes and Vibration Perception Threshold on the Severity of Erectile Dysfunction in Patients with Type 2 Diabetes Mellitus

Acta Endo (Buc) 2022, 18 (2): 174-180
doi: 10.4183/aeb.2022.174

Background. Erectile dysfunction(ED) in men is a frequent under-reported complication of diabetes mellitus, which is becoming significant health problem worldwide. Aims. The study aims to determine the prevalence and risk factors for development of ED in North Indian patients with type 2 diabetes mellitus. Methods. We used international index of erectile function (IIEF-5) for the assessment of ED in 796 patients with type 2 diabetes mellitus. We recorded the age, duration of diabetes, glycemic status, body mass index, diabetes medications, microvascular and macrovascular complications. Results. The mean age of patients in the study was 49.38 ± 9.52 years. The prevalence of ED in patients with type 2 diabetes mellitus was 79.4%. Logistic regression analysis revealed that age, body mass index, glycemic control, insulin therapy, retinopathy and nephropathy was not significantly associated with erectile dysfunction in patients with type 2 diabetes mellitus. Duration of diabetes (OR = 1.054, 95% CI 1.007 to 1.102, P=0.023) and vibration perception threshold (OR = 1.071, 95% CI 1.042 to 1.102, P=0.000) were identified as key risk factors for development of ED. Conclusion. Duration of diabetes and peripheral neuropathy emerged as significant risk factors for development of severe erectile dysfunction.

Keywords: Erectile dysfunction, Type 2 diabetes mellitus, Peripheral neuropathy, Vibration perception threshold.

Correspondence: Saurabh Arora MD, Dayanand Medical College and Hospital, Endocrinology and Metabolism, Tagore Nagar, Ludhiana, Punjab, 141001, India, E-mail: