October - December 2022, Volume 18, Issue 4

Mazur OV, Palamarchuk VA, Tovkai OA, Kuts VV, Shidlovskyi VO, Sheremet MI, Levchuk RD, Morozovych II, Lazaruk OV, Cretoiu D

Predictors of Multifocal Papillary Thyroid Cancer. Do They Exist?

Acta Endo (Buc) 2022, 18 (4): 424-428
doi: 10.4183/aeb.2022.424

The aim of this study is to analyze and identify the main predictors that may indicate multifocal growth of PTC. Materials and methods. The main and control groups included patients with the category of malignant multifocal process T1-3mN0Mx (n=109) and unifocal T1- T3N0Mx (n=50) respectively, who underwent thyroidectomy with lymphadenectomy. Ultrasound characteristics of the nodes, tissue changes of the thyroid gland were taken into account. Results. Fibrous changes can be considered as one of the risk factors of the presence of additional PTC lesion. Discussion. There is no unambiguity in the definition of predictors of multifocal PTC growth. Conclusions. No clear predictors of multifocal PTC have been identified. It is advisable to improve the quality of ultrasound, to focus on single-focus PTC in patients with fibrinous changes in the thyroid gland at normal levels of TSH.

Keywords: thyroid carcinoma, multifocality, ultrasound diagnostics, predictors

Correspondence: Michael Ivanovich Sheremet MD, PhD, Bucovinian State Medical University, Surgeon #1, Golovna Str. 191/16, Chernivtsi, 58018, Ukraine, E-mail: mihayl71@gmail.com