April - June 2023, Volume 19, Issue 2

Duran R, Marakoglu K, Vatansev H, Kizmaz M, Saracligil, Aybatti E, Demirci V, Kebapcilar L

Evaluation of the Relationship between Medical Nutrition Treatment, PENTRAXIN-3, HSCRP and Body Composition Analysis in Type 2 Diabetic Patients

Acta Endo (Buc) 2023, 19 (2): 169-177
doi: 10.4183/aeb.2023.169

Objective. Medical Nutrition Therapy (MNT) is important in the treatment and regulation of diabetic patients. In this study, it was aimed to evaluate the effects of medical nutrition therapy on Pentraxin-3, hsCRP and body composition analysis in Type 2 diabetes patients (DM). Methods. This study included 160 individuals who were admitted and diagnosed with Type 2 DM. Laboratory, clinical, anthropometric and body composition parameters were obtained 3 months after baseline evaluation of the patients and the MNT was given by the dietitian. Results. After 3 months MNT, weight, body mass index, waist circumference, body fat weight, body fat ratio and visceral fat area (p<0.001), glucose (p<0.001), insulin (p=0.033), HOMA index (p=0.004), HbA1c (p<0.001), total cholesterol (p=0.001), LDL (p=0.008), ALT (p<0.001) and hsCRP (p<0.001) levels were significantly lower than they were before MNT. There wasn’t significant difference in triglyceride (p=0.509), HDL (p=0.079), Pentraxin-3 (p=0.706) levels and waist-to-hip ratio (p=0.802). The level of Framingham risk score after MNT was significantly lower (p<0.001). Conclusion. In this study, it was cocluded that MNT, applied to patients with Type 2 DM decreased cardiovascular risk and inflammation, contributed to the maintenance of glycemic control, and a significantly improved the body composition.

Keywords: type 2 diabetes mellitus, medical nutrition therapy, hsCRP, pentraxin-3

Correspondence: Muhammet Kizmaz MD, Department of Family Medicine, Medical Faculty, Selcuk University, 42075, Konya, Turkey, E-mail: muhammet-kizmaz@hotmail.com