October - December 2023, Volume 19, Issue 4

Wasnik DV, Khot RS, Joshi PP, Rathod BD, Narang U, Ratnaparkhi C

Parathyroid Adenoma Presenting as Multiple Brown Tumors and Severe Asymptomatic Hypercalcemia

Acta Endo (Buc) 2023, 19 (4): 508-511
doi: 10.4183/aeb.2023.508

Introduction. Primary hyperparathyroidism may have several presentations, varying from an incidental asymptomatic biochemical finding to gastrointestinal, psychiatric, renal and bone manifestations. Brown tumors are rare non-neoplastic lesions because of abnormal bone metabolism. Herein, we describe a patient who presented with lytic bony lesions and severe asymptomatic hypercalcemia due to parathyroid adenoma. Case presentation. A 38-year-old male presented with multiple painful bony lesions over upper and lower limbs. Radiographs of long bones showed multiple lytic lesions with cortical thinning. Investigations revealed hypercalcemia and hyperparathyroidism. A radionuclide scan showed parathyroid adenoma. The patient was treated for hypercalcemia and a parathyroidectomy was performed. Conclusions. In a patient presenting with multiple bony swellings and asymptomatic hypercalcemia, hyperparathyroidism should be suspected. Parathyroid adenoma is a treatable cause of primary hyperparathyroidism.

Keywords: asymptomatic hypercalcemia, brown tumors, hyperparathyroidism, parathyroid adenoma.

Correspondence: Dhiraj Vilas Wasnik MD, All India Institute of Medical Sciences, Dept. of General Medicine - Nagpur, Mihan, Nagpur, Maharashtra, 441108, India, E-mail: wasnikdhiraj257@gmail.com