ACTA ENDOCRINOLOGICA (BUC)

Context. In this study we compared daily calorie restriction, and intermittent calorie restriction in overweight and class 1 obese patients. Findings are these diets correct metabolic parameters and intermittent calorie restriction diet regimen increases muscle strength. Aim. We investigated the effects on metabolic, anthropometric values and muscle in Intermittent Fasting (IF) and Continuous Calorie Restriction (CCR) groups in adult overweight and class 1 obese patients. Material and Methods. The patients were randomly divided into 3 groups: IF group (n=23), CCR group (n=21), and control group (n=22). Fat mass, and basal metabolic rate were recorded. Fat-Free Mass Index (FFMI) was calculated. Handgrip strength was measured. Walking speed test was performed. The 'International Physical Activity Questionnaire‘ was administered to the patients. Weight, body mass index, fat mass, muscle mass, FFMI, waist circumference, right and left arm circumference, right and left calf circumference values decreased significantly and similarly compared to the beginning at the end of 6 months in the IF and CCR groups (p<0.05). A statistically significant increase was found in hand grip strength test measurements in the IF groups. Conclusions. IF and CCR diets enhance metabolic functions while reducing muscle mass. Despite this decrease, the IF diet increases muscular strength.