ACTA ENDOCRINOLOGICA (BUC)

The International Journal of Romanian Society of Endocrinology / Registered in 1938

in ISI Thomson Master Journal List

Acta Endocrinologica(Bucharest) is live in PubMed Central

Year Volume Issue First page
10.4183/aeb.
Author
Title
Abstract/Title
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  • Case Report

    Radojkovic D, Stojanovic M., Pesic M., Radojkovic M., Radenkovic S., Radjenovic T.P., Stevic M., Stankovic I

    Clinically “silent” giant pheochromocytoma. case report

    Acta Endo (Buc) 2013 9(1): 121-129 doi: 10.4183/aeb.2013.121

    Abstract
    Context. Clinically „silent“ pheochromocytomas are very rare tumors. Objective. We present a patient with incidentally discovered, asymptomatic benign pheochromocytoma and discuss its presentation and management. Conclusion. Considering the increasing incidence of adrenal incidentalomas and, therefore, pheochromocytomas too, every incidentally found adrenal mass has to be carefully examined regardless of its clinical presentation in order to prevent fatal oversight of possible secreting nature and/or malignant potential of the lesion and to ensure an adequate curable treatment.
  • Endocrine Care

    Stojanovic SS, Arsenijevic NA, Djukic A, Djukic S, Zivancevic Simonovic S, Jovanovic M, Pejnovic N, Nikolic V, Zivanovic S, Stefanovic M, Petrovic D

    Adiponectin as a Potential Biomarker of Low Bone Mineral Density in Postmenopausal Women with Metabolic Syndrome

    Acta Endo (Buc) 2018 14(2): 201-207 doi: 10.4183/aeb.2018.201

    Abstract
    Context. Adiponectin is an abundant adipokine, which has antiinflammatory, anti-atherosclerotic and vasoprotective actions, and potential antiresorptive effects on bone metabolism. It seems to be directly involved in the improvement and control of energy homeostasis, protecting bone health and predicting osteoporotic fracture risk. Objective. To examine the relationship between adiponectin level and bone mineral density (BMD) in postmenopausal women with metabolic syndrome (MetS) and low BMD, and to estimate the prognostic significance of adiponectin in osteoporosis. Design. Clinical-laboratory cross-sectional study including 120 middle-aged and elder women (average 69.18±7.56 years). Subjects and Methods. The anthropometric parameters were measured for all examinees. Lumbar spine and hip BMD, as well as body fat percentage, were measured using a Hologic DEXA scanner. In all subjects serum adiponectin concentration was measured by ELISA method. Results. The level of adiponectin was significantly positively correlated with BMD-total, BMD of the lumbar spine and BMD of the femoral neck (r=0.618, r=0.521, r=0.567; p<0.01). Levels of adiponectin and BMD are significantly lower in post-menopausal women with MetS and osteoporosis compared to patients with osteopenia (856.87±453.43 vs. 1287.32±405.21 pg/mL, p<0.01; BMD, p<0.05), and the highest values in healthy examinees. A cutoff value of adiponectin level for osteoporosis/osteopenia was 1076.22/1392.74 pg/mL. Conclusions. Post-menopausal women with MetS have significantly lower adiponectin level and low BMD compared to healthy examinees. Adiponectin may be an early, significant and independent predictor of developing osteoporosis in women with MetS, especially in postmenopausal period.