October - December 2006, Volume 2, Issue 4

Dumitrescu C, Ionescu M, Ioachim D, Procopiuc C, Popa M

Childhood thyroid carcinoma: two cases with unusual associations

Acta Endo (Buc) 2006, 2 (4): 457-463
doi: 10.4183/aeb.2006.457

Thyroid carcinoma is rare in children and adolescents and has a relatively favorable prognosis. As in adults, the incidence in girls is double than in boys. It has a little risk of mortality, but a high risk of recurrence. Patients younger than 15 years old at diagnosis are considered more likely to have more extensive tumor at diagnosis than patients who are 15 years and older. We report two patients: an 11 years old girl with Fallot tetrallogy and papillary thyroid cancer and a 13 years old girl with Graves’ disease treated with antithyroid drugs for three years and thyroidectomized at 17 years old with an incidental thyroid microcarcinoma. Those unusual associations are discussed regarding therapy and follow-up issues.

Keywords: childhood thyroid carcinoma, Fallot tetrallogy, Graves’ disease

Correspondence: Cristina Dumitrescu, MD, PhD, C.I.Parhon Institute of Endocrinology, 34- 36 Aviatorilor Blvd, Bucharest 1, Romania, e-mail: cristina50dum@yahoo.com