April - June 2012, Volume 8, Issue 2

Stojanic RM, Zivaljevic V, Diklic A, Kalezic N, Kazic M, Sabljak V, Paunovic I

The Solitary Bone Metastasis as a First Sign of Papillary Thyroid Cancer

Acta Endo (Buc) 2012, 8 (2): 289-294
doi: 10.4183/aeb.2012.289

Context. Tumors associated with thyroid gland are relatively rare. Papillary thyroid cancer (PTC) represents the most\r\nfrequent thyroid neoplasm, and it has almost in all of the cases favorable prognosis. In the largest number of the cases, PTC remains within the thyroid gland or it gives the\r\nlymphogenic metastasis in the cervical lymph nodes and, extremely rare, it results in hematogenic metastasis.\r\nObjective. To present a case of a patient who had a distant secondary deposit in pelvic bone and sacral bone as a first sign of the PTC.\r\nSubjects and Methods. A 56 year old male was presented in this report.\r\nResults. After intensive hip pain, patient was diagnosed with osteolytic lesion in sacral and left pelvic bone. After aspiration biopsy, macroscopic analysis and imunohistochemistry, diagnosis of PTC was set. Patient has undergone total thyroidectomy, two doses of radioiodine\r\nwere applied and secondary deposit palliative radiotherapy as well.\r\nConclusions. The total thyroidectomy is the first line therapy in the PTC patients for primary tumors, while the therapy for the secondary deposits requires surgical\r\nprocedures combined with other means of treatment.

Keywords: Thyroid, Cancer, Surgery

Correspondence: Radenko Milan Stojanic, Clinic for Endocrinology, Clinical Center of Serbia - Center for Endocrine Surgery, Koste Todorovica 8 Belgrade 11000, Serbia, Email: radenkos84@hotmail.com