The International Journal of Romanian Society of Endocrinology / Registered in 1938

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  • Case Report

    Stojanic RM, Zivaljevic V, Diklic A, Kalezic N, Kazic M, Sabljak V, Paunovic I

    The Solitary Bone Metastasis as a First Sign of Papillary Thyroid Cancer

    Acta Endo (Buc) 2012 8(2): 289-294 doi: 10.4183/aeb.2012.289

    Context. Tumors associated with thyroid gland are relatively rare. Papillary thyroid cancer (PTC) represents the most\r\nfrequent thyroid neoplasm, and it has almost in all of the cases favorable prognosis. In the largest number of the cases, PTC remains within the thyroid gland or it gives the\r\nlymphogenic metastasis in the cervical lymph nodes and, extremely rare, it results in hematogenic metastasis.\r\nObjective. To present a case of a patient who had a distant secondary deposit in pelvic bone and sacral bone as a first sign of the PTC.\r\nSubjects and Methods. A 56 year old male was presented in this report.\r\nResults. After intensive hip pain, patient was diagnosed with osteolytic lesion in sacral and left pelvic bone. After aspiration biopsy, macroscopic analysis and imunohistochemistry, diagnosis of PTC was set. Patient has undergone total thyroidectomy, two doses of radioiodine\r\nwere applied and secondary deposit palliative radiotherapy as well.\r\nConclusions. The total thyroidectomy is the first line therapy in the PTC patients for primary tumors, while the therapy for the secondary deposits requires surgical\r\nprocedures combined with other means of treatment.
  • Images in Endocrinology

    Tausanovic KM, Zivaljevic V, Paunovic IR

    Vertebral Metastasis as First Sign of Thyroid Papillary Microcarcinoma

    Acta Endo (Buc) 2014 10(4): 705-706 doi: 10.4183/aeb.2014.705