April - June 2021, Volume 17, Issue 2

Gao M, Chao L, Wang H, Peng R, Xiao X, Wang G, Gao Y, Wang G, Sun C

Correlation between Subclinical Hypothyroidism and Dyslipidemia in Women in Northeast China

Acta Endo (Buc) 2021, 17 (2): 282-285
doi: 10.4183/aeb.2021.282

Context. It is well known that thyroid hormones are important, being involved in affects the metabolism of carbohydrate, protein, lipids. The relationship between thyroid hormones and lipid metabolism is the focus of recent research. Objective. To investigate the relationship between subclinical hypothyroidism and lipid metabolism in women. Design. We conducted an epidemiological survey of thyroid diseases among women in Northeast China from September 2014 to December 2014. Subjects and Methods. A total of 1397 women underwent physical examinations and laboratory tests for thyroid function and lipid metabolism. Results. We found that the detection rate of subclinical hypothyroidism was 13.03%. Patients with subclinical hypothyroidism showed significantly higher levels of triglyceride (1.69±1.9 vs. 1.45±1.4) and the risk of hyper triglyceridemia in women with thyroid stimulating hormone (TSH) levels ≥10mIU/L was 4.96-fold higher compared with that in the normal population (P<0.01). Conclusion. Disorders of lipid metabolism in women with subclinical hypothyroidism show a direct correlation with the level of TSH, and the risk of hyper triglyceridemia is significantly increased when the level of TSH ≥10mIU/L.

Keywords: subclinical hypothyroidism, dyslipidemia, thyroid stimulating hormone

Correspondence: Chenglin Sun MD, Jilin University First Hospital- Endocrinology, 71 Xinmin Street of Changchun, Changchun, Jilin, 130000, China, E-mail: clsun213@163.com. Guixia Wang MD, Jilin University First Hospital- Endocrinology, 71 Xinmin Street of Changchun, Changchun, Jilin, 130000, China, E-mail: gxwang6688@yahoo.com.