January - March 2024, Volume 20, Issue 1

Zhou R

Parathyroid Carcinoma with Lack of Clinical Symptoms: A Case Report and Review of Literature

Acta Endo (Buc) 2024, 20 (1): 103-106
doi: 10.4183/aeb.2024.103

Context. Parathyroid carcinomas (PC) are rare. Imaging and laboratory tests can suggest a diagnosis of PC, but pathological examination is ultimately required to confirm the diagnosis. Objective. The clinicopathologic data, diagnosis, and treatment of a case of PC diagnosed in our hospital in 2022 are retrospectively summarized in this case report to improve the understanding, diagnosis, and differential diagnosis of this disease. Design. Case report. Subjects and Methods. Herein, we present the case of a 35-year-old man who presented with imaging and laboratory findings suggestive of a parathyroid neoplasm. Results. The patient underwent radical resection of the tumor, which was histopathologically diagnosed as PC. Conclusion. In this case, the clinical manifestations of PC were insidious, and the histological features had to be differentiated from tumors, such as parathyroid adenoma, clear cell renal cell carcinoma, and medullary thyroid carcinoma; thus, its diagnosis was challenging.

Keywords: male, adult, carcinoma, renal cell, thyroid gland, parathyroid neoplasms, thyroid cancer, medullary.

Correspondence: Ran Zhou MD, The Second People’s Hospital of Yibin, No. 96, North Street, Cuiping District, China, Yibin City 644002, China, E-mail: 121173041@qq.com